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IgG levels and susceptibility to HIV infection unrelated to the lung infection
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(Reuters Medical News) American researchers reported, Acquired immunodeficiency syndrome (AIDS) infection and reduce the antibody on pulmonary epithelial cells could not explain the increased susceptibility to bacterial infection. In fact, AIDS infection in lung epithelial cells and IgG2 antibody IgG solution AIDS infection than those without the antibodies high.

Ohio State University in the United States Mark D.. Wewers, and her colleagues examined 23 cases of AIDS HIV-infected patients and 25 cases of infection in bronchoalveolar lavage fluid (BALF) and serum IgG and IgG 2 antibodies.

The researchers found. AIDS infection in BAL and IgG2 antibody IgG levels were higher than that of the control group. AIDS infection for an average of 0.19 mcg/mcg lung epithelial IgG levels. mcg/mcg 0.11 for the control group. 0.034mcg/mcg IgG2 level of infection in patients with AIDS. 0.014mcg/mcg control group. Serum antibody levels were consistent with the BAL, suggesting BAL IgG from serum. These results suggest that bacterial lung infection on the immune defects is unlikely to be caused by abnormal number of IgG. No research on lung antibody levels decline surprised currently detect the presence of pulmonary macrophages defects so prone to lung infection.


This article was posted on 2007-02-27

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