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Psoriatic arthritis treatment should also be paid to both the skin and joints, therapeutic purposes to inhibit inflammation, maintain and improve joint function. And acute appropriate rest, spiritual comfort and encouragement, with appropriate therapy can help alleviate the symptoms. then the appropriate joint function and muscle training. Should attach importance to the treatment of skin damage. Tong noteworthy is that the skin lesions disappeared, the joint is not necessarily a corresponding improvement in symptoms, but a considerable number of patients. joint symptoms and skin lesions, often better or even disappear.
Drugs, the use of non-steroidal anti-inflammatory drugs, with air - and analgesic effect of such drugs. Psoriatic arthritis is the most commonly used drug therapy light. Commonly used in the diclofenac sodium (supporting him), Yue Mei, MO than the music song, giving properly, naproxen, naproxen cycloheximide. They reduce swelling, pain, stiffness have a certain role.
Prednisone (prednisone), adrenocorticotropic hormone, psoriatic arthritis have significant effects especially for the disease, accompanied by joint swelling, fever, ESR increase, and the general treatment of patients control symptoms. But in the process of reducing drug can be repeated illness, long-term side effects of a larger application. Some of psoriatic patients after discontinuation of estrogen may increase, or even erythroderma. Therefore, the use of hormone therapy should be cautious, the general should not be easily applied. If only one or two joints involved early, can be used triamcinolone acetonide, Lee Limethason, Diprospan and other intra-articular injections.
For many patients with psoriatic arthritis aggravated sexual joints, an early application of slow-acting drugs, such as antimalarials, The agents, sulfasalazine, methotrexate, etc..
Psoriatic arthritis is the supreme will of chloroquine efficacy Application process of psoriatic skin damage caused but the reaction has not increased significantly, as selective treatment. 0.25-0.5 grams daily. The main side effect is cause retinopathy. Therefore, medication, regular checks noticed hydroxychloroquine than chloroquine efficacy, side effects. their daily dose of 0.2-0.4 grams.
Methotrexate has been established for the effective treatment of psoriatic arthritis medicine for almost 40 years. It will improve both the skin and joint disease in 2-8 weeks treatment, the patient could 42%"90% effect. Its use following two :
¢Ù methotrexate once a week, the initial dose of 5 mg, 2.5 mg per week to increase 15-25 mg per week until serving. When conditions improved gradually decreasing to maintain the minimum effective dose.
Second, methotrexate 10 mg intramuscular injection or intravenous infusion once a week, if serious condition, without adverse reaction, to be gradually increasing doses of 20-25 mg per week. disease control and then gradually decrease to be 30 mg per week to maintain.
MTX regimen generally 3-5 months or longer, oral and intramuscular injection, intravenous considerable effect. The side effects of liver toxicity, neutropenia or stomatitis. Liver disease who have not applied. During treatment, the examination should be done regularly, and smoking, alcohol avoidance.
The agents for the treatment of psoriatic arthritis are already more than 30 years old, have a certain effect. The current use of oral formulations Switzerland have each 3 mg, twice daily.
In recent years, clinical trials have proven that effective sulfasalazine of psoriatic arthritis. 0.5-1 grams per day, three times. Side effects are nausea, diarrhea and drug allergy.
Retinoic acid on the disease effectively, aromatic retinoic acid (trade name YINXIELING) better. 0.5 mg per kilogram body weight per day use. Its main side effects are dry skin and lips chapped mucosa. Reversibility also can cause abnormal liver function and serum triglyceride (TG) increased. The drugs have teratogenic effects in pregnant women and breast-feeding women banned. Oral 8-methoxypsoralen, two hours after UVA irradiation, psoriatic arthritis for a certain effect.
Triptolide effective medicine for psoriatic arthritis. Common tripterygium wilfordii, each 10 mg three times a day. Pigmentation, leukopenia, abnormal liver function, side-effects such as amenorrhea.
Slow course of psoriatic arthritis, the severity of the disease and prognosis. According to research, patients with abnormal sexual 40%-57% destructive arthritis. 17% of the patients had five or more joint deformities, 11%-19% obviously disabled patients.
This article was posted on 2007-02-27
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