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Japanese encephalitis clinical
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22th day incubation period, generally 10 to 14 days. Monocyte-macrophage cells in the early virus reproduction, and then released into the blood, and most people are not symptomatic infection, However, elevated blood antibody, called subclinical infection. Some suffered mild respiratory symptoms; A very small number of patients, the virus through the blood-brain barrier causing central nervous system diseases. Encephalitis symptoms appeared.

Typical disease patients can be divided into four stages :

(1) Thermal early period

Onset 1-3 days, the temperature rose to 38"39 ¡æ 1-2 days, accompanied by headache, Chapter burnout and drowsiness, nausea, vomiting. Children can have respiratory symptoms or diarrhea.

(2) phase.

No. 4-10 days duration, into a polar phase, Noxious outstanding performance for systemic symptoms and the symptoms of brain damage.

1. High Fever

JE is an inevitable feature of the performance. The temperature is as high as 39-40 ¡ã C above. Light continues to 3-5 days, 7-10 days of the general, who re-up for several weeks. The higher the heat, longer-range is the more severe the disease.

2. Consciousness

1-3 days after the onset of the majority of people in varying degrees of consciousness, such as drowsiness, coma. JE early lethargy often specific to the performance. Usually 7-10 days to return to normal, sustained serious over in January.

3. Eclampsia, or convulsion

JE is one of serious symptoms. Because brain lesions with different levels of performance can be mild hand, foot, facial disfigurements or convulsions. to be systemic or generalized convulsive fits ankylosing cramps, sustained a few minutes to tens of minutes.

4. Respiratory Failure

Japanese encephalitis is the most serious symptoms, as well as an important cause of death. Is the central respiratory failure may damage the respiratory center, cerebral edema, cerebral herniation, and other causes of hyponatremic encephalopathy. Of respiratory superficial, not the whole rhythm, double suction, sighing respiration, apnea, as well as Chao's breathing stopped breathing. Central respiratory failure and peripheral respiratory failure may exist. Peripheral to the main difficulty in breathing respiratory failure, respiratory rate changes, breathing movement weakened, cyanosis, but always tidy rhythm. High fever, seizures and respiratory failure triple acute encephalitis syndrome is often inter-related and their influence on each other, exacerbating the disease.

5. Meningeal irritation

Older children and adults have different levels of meningeal irritation. Infant more unnecessary performance, but a former chimney uplift.

6. Other signs and symptoms of nervous system

If the pyramidal tract damage, often spastic paralysis of limbs, muscle tension increased, Babinski patients. Few could have showed soft. Cerebellum and oculomotor nerve involvement, nystagmus may occur, the pupil to expand or narrow ranges, light a slow response; Nerve damage frequent urinary retention, incontinence; Anti-shallow body weaken or disappear, deep hyperreflexia or disappeared.

7. Other

Some circulatory failure may occur in patients with encephalitis showed decreased blood pressure, pulse rate fine. Sometimes gastrointestinal bleeding. The temperature dropped in the end most of the patients, physicians, Recovering. Brain damage or serious complications due to a small number of patients died from heavy current.

(C) recovery

After 2-5 days to a very normal body temperature in a coma to clear, Some patients in a spirit of a short-term "sluggish phase", after the speech, expression, movement and neurological reflex gradually returning to normal. Some patients recover more slowly, need 1-3 months. Performance of individual patients with severe low heat, sweating, aphasia, such as paralysis. But aggressive treatment, often in the six months to restore.

(D) The period of aftermath

Despite aggressive treatment, the incidence of some patients still have six months after the nerve symptoms. as sequels. About 5"20% rate. With aphasia, the most common mental disorders and paralysis. To continue active treatment, the recovery is still expected to a certain extent.

According to the severity, can be divided into four types : JE

1. Light

Patients mind always clear, and there were varying degrees lethargy, the general modified, meningeal irritation not obvious. 38"39 ¡ã C in temperature usually more in a week to restore, recovery without symptoms.

2. Medium

A sense of obstacles such as drowsiness or light coma. Abdominal reflexes and cremaster reflex. Occasional twitch. Normal body temperature of around 40 ¡ã C, and the course of about 10 days, and more


This article was posted on 2007-02-27

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