(1) to strengthen care
keep quiet, to reduce the moving head were lying or the right, head - and-shoulder slightly heel 30 degrees. 35.5"36.5 maintained in the temperature range between children. That is, symptoms at birth, breastfeeding are advised to defer. Oxygen, and timely cleaning respiratory secretions. Liquid volume control, not less Ning, 50"60ml/kg daily.
(B) symptomatic treatment
A anticonvulsant therapy "First of all, pay attention to the treatment of neonatal seizures" HIE may exist in the metabolic disorders such as hypoglycemia, hypocalcemia, hypomagnesemia, hyponatremia and so immediate. Once metabolic disorder caused by the seizures is not for use anticonvulsant drugs. In principle, to choose a drug, the dose should be sufficient, or alternate use of the two drugs. During regular monitoring of blood concentration of drug administration, after close observation of medication to stop seizures, quiet sleep, breathing rhythm steady, finger bending tension to a certain degree.
1. Phenobarbital
control neonatal convulsions preferred. Giving first load 15"20mg/kg, intramuscular injection or intravenous injection slow. If not control seizures can give 5mg/kg every 10-15 minutes, until the seizures stop. The total amounts of 30mg/kg. Control seizures after being given 12-24 hours before the start of the volume, according to the daily 5mg/kg. Two intravenous or intramuscular injection once every 12 hours, for 2-3 days after oral administration to maintain. Notes, when combined with the stability of respiratory depression.
2. Stability
status for the treatment of neonatal convulsions drug of choice, 0.3"0.5mg/kg for each dose, intravenous. Drug half-life of 15 minutes, through the blood-brain barrier quickly, it will soon disappear. So therefore be 2.0 minutes after repeated use, can be applied 3-4 times a day. When the convulsions of the cut-off can be difficult to control daily 3"12mg/kg continuous intravenous infusion.
B on the treatment of cerebral edema
1.20% mannitol
each 0.25"0.5g 2/kg (1.25"2.5ml/kg), a 6-hour intravenous injection or intravenous infusion. intracranial pressure and the level of consciousness can be used as indicators of the need for repeated injections.
2. Adrenocorticotropic hormone
a continued easing early cerebral edema, which can be used to reduce the duplication of mannitol. Common dexamethasone each 0.5"lmg/kg every 6-12 1 hour, 48 hours more than in the application, Gen attention within 48 hours after the decision to stop or reduce illness.
3. Control liquid
intracranial hypertension caused by cerebral edema, fluid control 60"80ml/kg daily volume. based electrolyte, plasma osmolality and urine, adjust to changes in body weight.
Cerebrovascular perfusion flow resumed C
when systolic pressure below 6.67kPa (ret) give intravenous dopamine (3"5ug/kg per minute) and dobutamine (per minute 2.5"10u 8.935), start with small doses of incremental large high volume.
D. improving brain cell metabolism
1. CDPC daily Department of Dermatology, 10% glucose solution 100"150ml, intravenously after paragraph 2, once a day until the symptoms improved or discharged from the hospital.
2. 1"2ml-day living brain by intravenous or intramuscular injection once a day, a course of 7-10 days. 2-3 treatment available.
3. Cytochrome C can be applied to other ATP, coenzyme A, etc..
E hyperbaric oxygen therapy "All" Hyperbaric oxygen available, the 1st day treatment, oxygen concentration from 90% to 100%, the pressure for esterification, every 2 hours As conditions for a continuous period of 5-10 times, and the ultrasound showed clinical symptoms of cerebral edema to disappear. Convulsions, you twitch stop after the hold steady pulse and breathing, combined with intracranial hemorrhage in stable condition after six hours of the hold.
(C) control bleeding
¢Ù live cable K 1"5mg/ times, intramuscular injection, one time a day, three days in a row.
¢Ú transfusion of fresh frozen plasma or whole blood daily 10"20mg/kg. Vitamin C, has been bleeding - or 6-amino acid.

This article was posted on 2007-02-27