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The differential diagnosis of haemorrhagic disease of the newborn
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One week after neonates with other causes of bleeding differential :

(1) : gastrointestinal bleeding and pharynx syndrome, congenital peptic ulcer. gastrointestinal infection and abnormal differentiation. Pharyngeal syndrome is a birth mother at birth canal swallow blood, amniotic fluid, such as blood, which happened shortly after vomiting. vomiting brown material, there should be a 38, but little blood, gastric lavage after antiemetic without coagulation disorders. In addition, the alkaline denaturation test can be used to identify maternal and child blood serum containing fetal hemoglobin (anti-alkaline). Maternal containing adult hemoglobin (weak alkaline resistance). Take water diluted vomit, rotating after 5 admission suspension, 1 plus 1% sodium hydroxide, 1-2 minutes observation, brown for mothers and infants to blood red. Early congenital peptic ulcer and gastric perforation, necrotizing enterocolitis while gastric involvement, may have hematemesis, hematochezia; production process hypoxia-induced acute stress ulcer, hematemesis, hematochezia, these diseases do not coagulation disorders.

(2) : bleeding injuries occur in the middle of the first delivery disclosed location, after having health. However, the disease often causes, or exist at the same time, increase mutual illness.

(3) : congenital idiopathic thrombocytopenic purpura in 1 week after internal bleeding, But platelets decreased significantly.

(4) other congenital or acquired coagulation disorder : ¢Ù other congenital lack of coagulation factor deficiency and congenital fibrinogen, both lifelong disease through blood transfusion although improved, still relapse, Lai takes specific diagnosis coagulation function, and for the temporary disease, a cure, and relapse. Second, various infections, scleroderma, pulmonary hemorrhage, bleeding caused by disseminated intravascular coagulation, were acquired. already there before the original incidence of bleeding, bleeding late in the newborn with the disease early, bleeding naturally different.

(5) Other : If umbilical cord ligation with a lack of bleeding, Umbilical bleeding caused by infection or granuloma identification. Menstrual bleeding with false identification. Rare hereditary hemorrhagic telangiectasia in the early neonatal bleeding.


This article was posted on 2007-02-27

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