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Hyaline membrane disease in the clinical and laboratory examination
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(1) symptoms and signs
after the birth of the general situation is good. 6-12 hours to emerge faster breathing, respiratory rate more than 60 per minute, Alar instigators. serious reduction in the number of breath, and then irregular breathing, apnea.
As the disease progresses, difficulty in breathing was heavier sexual appeared inspiratory and expiratory three concave levy sexual groans obvious cyanosis. slow, limb dystonia drop in the temperature did not rise, or pale complexion schungite body edema with ovulation. Thorax uplift at the beginning of the future with pulmonary atelectasis gradually worsened and the subsidence, particularly the Ministry of armpit more obvious. Reduce pulmonary respiratory distress. Heart rate began to increase rapidly after slowing down, the heart sounds from strong to weak, or left edge sternum can be heard heart, I-grade systolic murmur. Liver may be increased. Generally more serious illness, in the absence of artificial ventilation often died within three days. If survive three days without complications, as long as the positive where handling well, could resume.
(2) laboratory
due to bad ventilation, and arterial oxygen tension (PaO2) low. Carbon dioxide partial pressure (PaCO2) increases. Blood pH dropped lack of alkali (BE), the increase in the number of bicarbonate (HCO3-) decrease lower serum sodium, potassium early to normal, if sustained acidosis, hypoglycemia, bleeding, hypokalemia will temporarily increase calcium significantly decreased after 72 hours regular.
(C) X-ray inspection "significantly lower transparency" two lungs, Dot shadow can be seen even small particles (alveolar collapse and did not know) and reticular shadow (the bronchioles and the over-inflated lung foam tube) features. Because there is no advanced alveolar air, the purpose of facilitating the integration of alveolar formation of real change, trachea and bronchi were still filling the air. it shows a transparent tube inflated levy. Inflatable done to the section of the trachea and bronchial and peripheral trachea, similar bald leaf bifurcation branches.
Giedion according to the severity of the illness into four categories :
Class I : grainy shadow of the only minor changes;
Levy : bronchial inflatable grade crossing cardiac risk;
Level 3 : There were further aggravated heart phrenic blurred;
Class IV : increased density generally referred to as "white lung."


This article was posted on 2007-02-27

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